Study: Suppressing Two Gene-silencing Enzymes May Hold Promise in FA
Schematic diagram of the FXN and GFP genes containing intronic GAA·TTC... | Download Scientific Diagram
Models of FXN gene silencing in FRDA. (A) Unaffected individuals, who... | Download Scientific Diagram
Gene regulation and epigenetics in Friedreich's ataxia - Yandim - 2013 - Journal of Neurochemistry - Wiley Online Library
Structure of the FXN gene and transcription maps. The structures of the... | Download Scientific Diagram
New breakthrough in the fight against Friedreich's ataxia
Gene Transfer of Brain-derived Neurotrophic Factor (BDNF) Prevents Neurodegeneration Triggered by FXN Deficiency: Molecular Therapy
4: FXN gene structure including exons, intron and the promoter region.... | Download Scientific Diagram
Frontiers | Epigenetic-based therapies for Friedreich ataxia
Needles&Neurons on X: "In the FXN gene, a GAA sequence repeats between 7-22 times. In Friedreich ataxia, this GAA triplet of DNA code is expanded, sometime repeated hundreds of times due to
Ed Grabczyk, PhD - LSUHSC School of Medicine
Structure–Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe–S Assembly Complex | Biochemistry
Frataxin - Wikipedia
PDF] Friedreich ataxia : investigating the relationships between mismatch repair gene expression, FXN gene expression and GAA repeat instability in human and mouse cells and tissues | Semantic Scholar
Fig 3 | PLOS Genetics
Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich's ataxia patient cells - Journal of Biological Chemistry